positioning during polysomnography and drug‑induced sleep endoscopy, to determine the effective protrusive position for mandibular advancement device therapy Abstract Study objectives The aim of this pilot study was to evaluate the clinical effectiveness of subjective titration versus objectively guided titration during polysomnography (PSG) and drug-induced sleep endoscopy (DISE) in mandibular advancement device (MAD) therapy for patients with obstructive sleep apnea (OSA
Apnea (OSA) Abstract Introduction: The role of comorbidities in determining health-related quality of life (HRQL) in obstructive sleep apnea (OSA) pa-tients has not been thoroughly investigated. Commonly used comorbidity tools, such as Charlson Comorbidity Index (CCI), have been designed with mortality as the outcome variable. A new tool, the Functional Comorbidity Index (FCI), has been especially developed to assess the effect of comorbidities on the "physical functioning" s
with obstructive sleep apnea: A clinical study Abstract Statement of problem
Objective assessments of the effect of mandibular advancement device on patients with obstructive sleep apnea are lacking.
The purpose of this clinical study was to compare levels of serum tumor necrosis factor alpha (TNF-alpha), Epworth Sleepiness Scale score, and Berlin Questionnaire score in patients with mild to moderate obstructive sleep apnea before and after treatment with a mandibular
apnea for maxillomandibular advancement Abstract STUDY OBJECTIVES:
(1) To investigate if drug-induced sleep endoscopy (DISE) findings are predictive of surgical response for patients undergoing maxillomandibular advancement (MMA) for obstructive sleep apnea (OSA) and (2) to investigate the predictive value of the jaw thrust maneuver during DISE in terms of surgical response to MMA.
A retrospective cohort study was conducted in patients with OSA who underwent a baseli
adults during sleep Abstract Background: Oral appliances (OAs) are generally designed to displace the mandible anteriorly and downward, to increase the airway patency. The present study aimed to examine the relationship between genioglossus (GG) muscle activity and mandibular position, considering both anterior and vertical displacements during sleep. Methods: Seven healthy male adults aged 29.4 ± 1.99 years were evaluated. Maxillary and mandibular OAs were fabricated from 2-
sleep apnea with a mandibular advancement device Abstract Purpose: To compare the short-term treatment effect of a mandibular advancement device (MAD) with and without previous drug-induced sleep endoscopy (DISE) on polysomnography (PSG) and other sleep apnea-related treatment outcomes (Short Form Health Survey [SF-36] and Epworth Sleepiness Scale [ESS]) among adults with mild, moderate, and severe obstructive sleep apnea (OSA). We hypothesized that using DISE would improve t
A systematic review of randomised controlled trials with meta-analysis and meta-regression Abstract Background: Mandibular advancement devices (MADs) are used as an alternative to continuous positive airways pressure to treat obstructive sleep apnoea (OSA) patients, but to date, specific data on the adherence to MAD therapy are lacking.
Objectives: The aim of the present systematic review was to investigate the dropout rate and adherence of OSA patients to different custom-ma
Oral appliance therapy (OAT) is a proven, effective treatment for obstructive sleep apnea (OSA); however, it can only be effective when it is used, which is why compliance – “the extent to which a patient’s behaviors match the prescriber’s recommendations”1 – is a necessary component of OAT. Over the years, qualified dentists have individually used various metrics to define a patient’s compliance. Currently, there is no standardized definition for oral appliance therapy (OAT)
Precision of a high-resolution pulse oximeter in screening for sleep-disordered breathing Abstract Purpose: High-resolution pulse oximetry (HRPO) may offer a low-cost and simple screening option for sleep-disordered breathing (SDB) that could be vitally important in rural areas with limited healthcare resources and specialty care. Our team hypothesized that application of this technology to a broad cohort of rural dwelling hospitalized individuals would demonstrate congruence
Implications for pathogenesis, treatment and future research directions Clinical Review
A systematic review and meta-analysis of upper airway sensation in obstructive sleep apnea – Implications for pathogenesis, treatment and future research directions.
Impaired upper airway sensation may contribute to obstructive sleep apnea (OSA) pathophysiology and could represent a therapeutic target. However, the extent of impaired sensation and its functional role in OSA pathogenesis r