Current Perspectives in Treatment of Obstructive Sleep Apnea with Mandibular Advancement Devices: A Narrative Review
This narrative review intends to provide a thorough analysis of the effectiveness, and comparison of the mono-block vs duo-block Mandibular Advancement Devices (MAD) and the potential side effects of these devices in managing Obstructive Sleep Apnea (OSA).
Mechanistic links between obstructive sleep apnea, cellular senescence and aging: The role of cardiometabolic dysfunction
While senescence plays roles in tissue repair, its accumulation also drives chronic inflammation and immune dysregulation. The connection between OSA, senescence, and aging remains complex and underexplored. Mechanisms like the senescence-associated secretory phenotype (SASP), impaired immune surveillance, and reduced regenerative capacity may contribute to OSA-related morbidity.
Detection of sleep apnea using only inertial measurement unit signals from apple watch: a pilot-study with machine learning approach
This study presents a method for detecting sleep apnea using data from the Apple Watch’s inertial measurement unit (IMU).
Adenotonsillectomy vs Watchful Waiting in Pediatric Mild to Moderate Obstructive Sleep Apnea
Objective To investigate whether ATE is more effective than WW for treating otherwise healthy children with mild to moderate OSA. This randomized clinical trial (RCT) of young children investigated the benefit of ATE compared with watchful waiting (WW) after 3 years
Short- and long-term effects of mandibular advancement device therapy for obstructive sleep apnea on temporomandibular disorders: A systematic review and meta-analysis
This systematic review and meta-analysis investigated the effects of mandibular advancement device (MAD) therapy on temporomandibular disorders (TMDs) in patients with obstructive sleep apnea (OSA).
Prediction of non-responders to oral appliance treatment of obstructive sleep apnea: a pilot study
Several clinically available variables have been identified as predictors of non-response to oral appliance (OA) treatment, including endotypical traits such as severe upper airway collapsibility, unstable ventilatory control, and low arousal threshold. This study aimed to identify potential predictors of non-response to OA treatment in patients with OSA non-adherent to treatment with positive airway pressure.
Can the use of morning occlusal guides after oral sleep appliances cause root resorption similar to orthodontic jiggling?
Objective: To evaluate root length changes associated with the use of mandibular advancement devices (MADs) to treat obstructive sleep apnea (OSA), in conjunction with morning occlusal guides.
Assessment of the causal association between obstructive sleep apnea and telomere length: a bidirectional mendelian randomization study
A plethora of observational studies has established a significant correlation between Obstructive Sleep Apnea (OSA) and Telomere Length (TL). Nevertheless, a universal consensus on precise causal association and its directionality has not yet been achieved. To shed light on this, we employed Mendelian Randomization (MR) to investigate the bidirectional causal association between OSA and TL.
Adherence and Side Effects Among Patients Treated With Oral Appliance Therapy for Obstructive Sleep Apnea
The aim of this study was to evaluate the level of patient knowledge and concern for the consequences of untreated OSA, perceived partner satisfaction, and reported adverse effects, and relate these to patient adherence to OAT.
Dental Sleep Medicine Standards for Screening, Treatment, and Management of Sleep-Related Breathing Disorders in Adults Using Oral Appliance Therapy: An Update
Oral appliance therapy is a proven, effective treatment for obstructive sleep apnea (OSA) and snoring. With more than 54 million adults having OSA in the United States, dentists play an integral role in increasing access to care for those with undiagnosed and untreated OSA.
